![Statistical controversies in clinical research: building the bridge to phase II—efficacy estimation in dose-expansion cohorts - ScienceDirect Statistical controversies in clinical research: building the bridge to phase II—efficacy estimation in dose-expansion cohorts - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0923753419322458-gr1.jpg)
Statistical controversies in clinical research: building the bridge to phase II—efficacy estimation in dose-expansion cohorts - ScienceDirect
![Translational phase I study with biomarker-defined end points. Phase I... | Download Scientific Diagram Translational phase I study with biomarker-defined end points. Phase I... | Download Scientific Diagram](https://www.researchgate.net/publication/264640460/figure/fig1/AS:282055268159519@1444258624826/Translational-phase-I-study-with-biomarker-defined-end-points-Phase-I-oncology-studies.png)
Translational phase I study with biomarker-defined end points. Phase I... | Download Scientific Diagram
![Phase 1A/1B dose-escalation and -expansion study to evaluate the safety, pharmacokinetics, food effects and antitumor activity of pamiparib in advanced solid tumours | British Journal of Cancer Phase 1A/1B dose-escalation and -expansion study to evaluate the safety, pharmacokinetics, food effects and antitumor activity of pamiparib in advanced solid tumours | British Journal of Cancer](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41416-021-01632-2/MediaObjects/41416_2021_1632_Fig2_HTML.png)
Phase 1A/1B dose-escalation and -expansion study to evaluate the safety, pharmacokinetics, food effects and antitumor activity of pamiparib in advanced solid tumours | British Journal of Cancer
![emDOCs.net – Emergency Medicine EducationPush-Dose Vasopressors: An Update for 2019 - emDOCs.net - Emergency Medicine Education emDOCs.net – Emergency Medicine EducationPush-Dose Vasopressors: An Update for 2019 - emDOCs.net - Emergency Medicine Education](https://i0.wp.com/www.emdocs.net/wp-content/uploads/2019/04/Screen-Shot-2019-04-21-at-5.23.21-PM.png?fit=1576%2C1064&ssl=1)
emDOCs.net – Emergency Medicine EducationPush-Dose Vasopressors: An Update for 2019 - emDOCs.net - Emergency Medicine Education
![Phase 1A/1B dose-escalation and -expansion study to evaluate the safety, pharmacokinetics, food effects and antitumor activity of pamiparib in advanced solid tumours | British Journal of Cancer Phase 1A/1B dose-escalation and -expansion study to evaluate the safety, pharmacokinetics, food effects and antitumor activity of pamiparib in advanced solid tumours | British Journal of Cancer](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41416-021-01632-2/MediaObjects/41416_2021_1632_Fig1_HTML.png)
Phase 1A/1B dose-escalation and -expansion study to evaluate the safety, pharmacokinetics, food effects and antitumor activity of pamiparib in advanced solid tumours | British Journal of Cancer
![Designing Dose-Finding Phase I Clinical Trials: Top 10 Questions That Should Be Discussed With Your Statistician | JCO Precision Oncology Designing Dose-Finding Phase I Clinical Trials: Top 10 Questions That Should Be Discussed With Your Statistician | JCO Precision Oncology](https://ascopubs.org/na101/home/literatum/publisher/asco/journals/content/po/2021/po.2021.5/po.20.00379/20210128/images/large/po.20.00379t2.jpeg)
Designing Dose-Finding Phase I Clinical Trials: Top 10 Questions That Should Be Discussed With Your Statistician | JCO Precision Oncology
![Inter-patient and intra-patient dose escalation strategy. Patients were... | Download Scientific Diagram Inter-patient and intra-patient dose escalation strategy. Patients were... | Download Scientific Diagram](https://www.researchgate.net/publication/46403694/figure/fig2/AS:667189245931545@1536081720859/Inter-patient-and-intra-patient-dose-escalation-strategy-Patients-were-sequentially.png)
Inter-patient and intra-patient dose escalation strategy. Patients were... | Download Scientific Diagram
![Statistical controversies in clinical research: building the bridge to phase II—efficacy estimation in dose-expansion cohorts - ScienceDirect Statistical controversies in clinical research: building the bridge to phase II—efficacy estimation in dose-expansion cohorts - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0923753419322458-gr3.jpg)
Statistical controversies in clinical research: building the bridge to phase II—efficacy estimation in dose-expansion cohorts - ScienceDirect
![Traditional sequential phase versus seamless expansion trial design. a... | Download Scientific Diagram Traditional sequential phase versus seamless expansion trial design. a... | Download Scientific Diagram](https://www.researchgate.net/publication/321285582/figure/fig2/AS:960010049835031@1605895640220/Traditional-sequential-phase-versus-seamless-expansion-trial-design-a-In-the-traditional.gif)
Traditional sequential phase versus seamless expansion trial design. a... | Download Scientific Diagram
![Frontiers | Dose accumulation for MR-guided adaptive radiotherapy: From practical considerations to state-of-the-art clinical implementation Frontiers | Dose accumulation for MR-guided adaptive radiotherapy: From practical considerations to state-of-the-art clinical implementation](https://www.frontiersin.org/files/MyHome%20Article%20Library/1086258/1086258_Thumb_400.jpg)
Frontiers | Dose accumulation for MR-guided adaptive radiotherapy: From practical considerations to state-of-the-art clinical implementation
![Bertrand Delsuc on X: "@BiotechRadar CUARt123 AML: RP2D definition, extensive DLT recording (differences vs ALL), dose expansion, risks assessment https://t.co/aDIcKjyNon" / X Bertrand Delsuc on X: "@BiotechRadar CUARt123 AML: RP2D definition, extensive DLT recording (differences vs ALL), dose expansion, risks assessment https://t.co/aDIcKjyNon" / X](https://pbs.twimg.com/media/CzqZ9KGXUAAXpDN.jpg)
Bertrand Delsuc on X: "@BiotechRadar CUARt123 AML: RP2D definition, extensive DLT recording (differences vs ALL), dose expansion, risks assessment https://t.co/aDIcKjyNon" / X
![Statistical controversies in clinical research: building the bridge to phase II—efficacy estimation in dose-expansion cohorts - ScienceDirect Statistical controversies in clinical research: building the bridge to phase II—efficacy estimation in dose-expansion cohorts - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0923753419322458-gr2.jpg)